Nanoarchitectronics: A versatile tool for deciphering nanoparticle interaction with cellular proteins, nucleic acids and phospholipids at biological interfaces

Mutalik, Sadhana P and Pandey, Abhijeet and Mutalik, Srinivas (2020) Nanoarchitectronics: A versatile tool for deciphering nanoparticle interaction with cellular proteins, nucleic acids and phospholipids at biological interfaces. International Journal of Biological Macromolecules, 151. pp. 136-158. ISSN 0141-8130

[img] PDF
8829.pdf - Published Version
Restricted to Registered users only

Download (917kB) | Request a copy

Abstract

Nano-Bio interface involves the dynamic interactions of nanomaterial and a living system. Association of nanotechnology and biology has been a valuable tool in improving the potentials of biomedical research. Exquisite structures of nanoparticles comparable in size with biomolecules and the unique possibility of tuning their chemical and physical functionality at small length scales make them more attractive for biological research. In this review,we comprehend Nano-Bio interactions at cellular levels and discuss parameters involved in determining nano-bio interactions. Techniques used for the characterization of nano-bio interactions have also been discussed. Applications of nanotechnology as a tool for manipulating cellular behaviors, studying important biological processes such as adhesion, morphology, and proliferation, and nanoparticles as nanoprobes and nanosensors have been discussed here. Knowledge of these interactions and processes at a cellular level will be useful for understanding the bioenergetics of subcellular organelle and might provide innovative ideas for designing newtools to enhance the understanding of cellular functions. Further, detailed information about the cellular and subcellular processes will be rather helpful in designing new nanocarriers and drug discovery

Item Type: Article
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Research > Research Center - Health Sciences
Depositing User: KMC Library
Date Deposited: 27 Jun 2020 08:08
Last Modified: 27 Jun 2020 08:08
URI: http://eprints.manipal.edu/id/eprint/155285

Actions (login required)

View Item View Item