Budihal, Dr. Suman Veerappa and Parwez, Khalid (2019) Optimisation of carbon nanotubes for advanced diagnosis and biomedical application. International Journal of Nanoparticles, 11 (3). pp. 217-238. ISSN 17532507
![]() |
PDF
DisplayPdf.pdf - Published Version Download (578kB) |
Abstract
Abstract: Nanomaterials have a broad spectrum of applications in biomedical fields. The carbon nanotubes (CNTs) are among the most versatile and well-characterised members of this group of materials. This review aims to discuss how to utilise CNTs as a diagnostic tool. Functionalisation with antibodies has gained significance in recent years among the various way of functionalisation of CNTs. Antibodies make their surface sensitive to surroundings for immuno-sensing. Surface passivation with other proteins is required to inhibit the non-specific binding of biomolecules on the hydrophobic carbon nanotube surface for ultrasensitive detection of biological species. CNT-based immuno-sensors provide excellent results with a promising sensitivity and reproducibility and, in combination with novel devices [such as a microfluidic electrochemical biosensor, nanoelectromechanical systems (NEMS), paper-based analytical devices (PADs), field effect transistors (FET)]. This combination offers an attractive analytical approach for the fast, low-cost, and accessible detection of trace prognostic biomarkers, microbial pathogens, environmental pollutants, and toxins. Keywords: nanomaterials; carbon nanotubes; functionalisation; biosensor; immuno-sensor; field effect transistors; FETs; micro electro mechan
Item Type: | Article |
---|---|
Uncontrolled Keywords: | Keywords: nanomaterials; carbon nanotubes; functionalisation; biosensor; immuno-sensor; field effect transistors; FETs; micro electro mechanical systems; MEMS; paper-based analytical devices; PADs; tissue engineering |
Subjects: | Medicine > KMC Mangalore > Physiology |
Depositing User: | KMCMLR User |
Date Deposited: | 03 Nov 2020 09:08 |
Last Modified: | 03 Nov 2020 09:08 |
URI: | http://eprints.manipal.edu/id/eprint/155480 |
Actions (login required)
![]() |
View Item |