Genetic diversity of Indian Plasmodium vivax isolates based on the analysis of PvMSP3ß polymorphic marker.

*, Anantabotla VM and *, Antony HA and *, Joseph NM and *, Parija SC and *, Rajkumari N and Kini, Dr. Jyoti R and *, Dr. Radhakrishna M and *, Nag VL and *, Gadepalli RS and *, Chayani N and *, Patro S (2019) Genetic diversity of Indian Plasmodium vivax isolates based on the analysis of PvMSP3ß polymorphic marker. Tropical Parasitology, 9 (2). pp. 108-114. ISSN 22295070

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Abstract

Abstract Background: Malaria is one of the major communicable diseases in India and worldwide. PvMSP3β is a highly polymorphic gene due to its large insertions and deletions in the central alanine-rich region, which, in turn, makes it a valuable marker for population genetic analysis. Very few studies are available from India about the genetic diversity of Plasmodium vivax based on PvMSP3β gene, and hence, this study was designed to understand the molecular diversity of the P. vivax malaria parasite. The accumulating epidemiological data provide insights into the circulating genetic variants of P. vivax in India, and ultimately benefits the vaccine development.

Item Type: Article
Uncontrolled Keywords: Genetic diversity, malaria, merozoite surface protein, merozoite surface protein-3β gene, Plasmodium vivax
Subjects: Medicine > KMC Mangalore > Pathology
Depositing User: KMCMLR User
Date Deposited: 03 Nov 2020 09:10
Last Modified: 03 Nov 2020 09:10
URI: http://eprints.manipal.edu/id/eprint/155495

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