Uncommon sites affected by a common disease: An autopsy study

Sahu, Dr. Kausalya Kumari and *, Dr. Pooja K S and Khadilkar, Dr. Urmila Niranjan and Pai, Dr. Radha R and Lobo, Dr. Flora D and Kini, Dr. Hema and Kini, Dr. Jyoti R (2019) Uncommon sites affected by a common disease: An autopsy study. Annals of Tropical Medicine and Public Health, 11 (4). pp. 130-132. ISSN 17556783

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ABSTRACT Context: Disseminated tuberculosis (DTB)is quite an uncommon entity. It is usually undetected as it can present in an atypically bland manner and go unsuspected. Aims: Our study aimed to determine the frequency of DTB in autopsies in our setting. Subjects and Methods: A retrospective study was done for a period of 6 years, i.e., from January 2009 to December 2015, wherein all the cases of DTB encountered in autopsy specimens were included in the study. Results: During the study period, we encountered 19 cases of DTB. In all 19 cases, the organs examined were lung (19/19 cases), liver (18/19 cases), kidney (12/19 cases), spleen (18/19 cases), pancreas (3/19 cases), heart (8/19 cases), and brain (5/19 cases). Caseating epithelioid granulomas were seen in all cases of lungs (19/19 cases), 16 cases in liver, 12 cases in kidney, and 17 cases in spleen, 2 cases of heart, and 2 cases of pancreas. DTB accounted for 1.3% (n = 19) of all autopsy cases, with the mean age being 41.35 years. The male: female ratio was 18:1. Eleven out of 19 cases were unknown bodies. Acid‑fast bacilli stain showed positivity in 10 cases. Conclusions: Despite recent technological advances in the diagnosis of tuberculosis, autopsy still remains an important complementary tool for identification of DTB.

Item Type: Article
Uncontrolled Keywords: Key words: Acid‑fast bacilli stain, autopsy, disseminated tuberculosis
Subjects: Medicine > KMC Mangalore > Pathology
Depositing User: KMCMLR User
Date Deposited: 03 Nov 2020 09:10
Last Modified: 03 Nov 2020 09:10
URI: http://eprints.manipal.edu/id/eprint/155512

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