Comparative analysis of the remineralization potential of CPP–ACP with Fluoride, Tri-Calcium Phosphate and Nano Hydroxyapatite using SEM/EDX – An in vitro study

*, Dr. CharishmaThimmaih and Shetty, Priya and *, Sowmya B and *, Dr. Srikant N and Thomas, Dr.Nithya Annie (2019) Comparative analysis of the remineralization potential of CPP–ACP with Fluoride, Tri-Calcium Phosphate and Nano Hydroxyapatite using SEM/EDX – An in vitro study. Journal of Clinical and Experimental Dentistry, 11 (12). e1120-e1126. ISSN 1989-5488

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Abstract

Abstract Background: In recent years, the non-invasive management of non cavitated caries lesions using remineralization systems to repair the enamel have received more attention from the scientific community. Aim: To quantitatively evaluate the remineralization potential of Casein Phosphopeptide-Amorphous Calcium phosphate-Fluoride(- CPP-ACPF), Tri-calcium phosphate(TCP) & Nano-hydroxyapatite(n-Hap) using Scanning Electron Microscopy(SEM) and Energy dispersive X-ray Analysis(EDX). Material and Methods: 40 enamel specimens were prepared, and immersed in demineralising solution at a pH of 4.4 for 96 hours at 37°C, to induce artificial carious lesions. Remineralization was carried out for a period of 30 days using CPP-ACPF, TCP, n-Hap. The specimens were evaluated for calcium and phosphorus content using SEM-EDX. Results: The Ca/P mass % after remineralization was significantly higher with CPP-ACP-F and TCP-F followed by n-Ha. Conclusions: CPP-ACP-F and TCP can promote significant remineralization of incipient carious lesions. These are excellent delivery vehicles available in a slow release amorphous form to localize calcium, phosphate and fluoride at the tooth surface

Item Type: Article
Uncontrolled Keywords: Key words: Remineralization, in vitro; CPP-ACP fluoride, Nano-hydroxyapatite, Tri-calcium phosphate, SEM/ EDX
Subjects: Dentistry > MCODS Mangalore > Oral Pathology
Dentistry > MCODS Mangalore > Pedodontics
Depositing User: KMCMLR User
Date Deposited: 03 Nov 2020 09:10
Last Modified: 03 Nov 2020 09:10
URI: http://eprints.manipal.edu/id/eprint/155517

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