Characteristics and correlates of poststroke depression: An Indian study

Praharaj, Samir Kumar (2019) Characteristics and correlates of poststroke depression: An Indian study. Indian Journal of Psychiatry, 61 (6). pp. 605-611. ISSN 0019-5545

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Abstract

Background: Post stroke depression adversely affects long term outcome of stroke and increases mortality risk. Few studies have looked into the comprehensive picture of post stroke depression in past.Aim: The current study aimed to look into the phenomenology, characteristic features and various correlates of post stroke depression.Method: 142 consecutive stroke patients aged 60 years or above, fulfilling the inclusion criteria were assessed.Sociodemographic and clinical data were gathered using a specially designed pro-forma. Depression, apathy and psychosis were assessed by Post stroke depression rating scale, Apathy Evaluation Scale, and Brief Psychiatric Rating Scale respectively. Groups (with or without major depression) were compared using Mann-Whitney U, chi square or Fisher’s exact test. One way ANOVA was conducted to see the relations of lesion location and laterality with various clinical parameters. Kaplan-Meier survival analysis was done to see the time to develop depression. The effect sizes were reported as r and partial eta squared.Results: Guilt was significantly higher (p<.05) with lesions in parietal lobe and remaining of middle cerebral artery territory. Catastrophic reaction (p<.05) and emotional dyscontrol (p<.05) were higher for diffuse lesions, periventricular lesions and lesions in frontal/occipital lobe. BPRS score, but not apathy, had a significant positive correlation with depression (Pearson’s r=.692). Mean time to develop depression after stroke was 28.34 (95% CI 22.37 to 34.31) months.Conclusions: Post stroke depression consists of various clinically important sub-components whose occurrence varies with different lesion locations. Post stroke depression is discriminable from apathy but is related to psychosis

Item Type: Article
Uncontrolled Keywords: Apathy; Depression; Stroke
Subjects: Medicine > KMC Manipal > Psychiatry
Depositing User: KMC Library
Date Deposited: 09 Oct 2020 08:33
Last Modified: 09 Oct 2020 08:33
URI: http://eprints.manipal.edu/id/eprint/155733

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