Effect of newtonian and non-newtonian flow in subject specific carotid artery

Kumar, Nithesh and Khader, Abdul S M and Pai, Raghuvir B and Kyriacou, Panicos and Khan, Sanowar and Prakashini, K and Rao, Srikanth D (2020) Effect of newtonian and non-newtonian flow in subject specific carotid artery. Journal of Engineering Science and Technology, 15 (4). pp. 2746-2763. ISSN 18234690

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Abstract

Advances in the numerical simulation techniques has immensely helped in the demonstrating the importance of blood flow through elastic arteries and evaluating the disease progression and flow dynamics of cardiovascular diseases such as atherosclerosis. The present work deals with a case study of a patient diagnosed with partial narrowing of entire cervical segment of Internal Carotid Artery (ICA), while Common Carotid Artery (CCA) and External Carotid Artery (ECA) appears to be normal. Subject specific 3D carotid bifurcation CAD model is generated based on CT-angio scan data using MIMICS-14.0 and numerical analysis is performed using Computational Fluid Dynamics (CFD) in ANSYSCFX-14.0. Pulsatile blood flow through the subject-specific artery is investigated to study the influence of rheology on the haemodynamics in the blood flow. The simulation results obtained through Carreau-Yasuda and Newtonian models are investigated. Flow behaviour observed during peak systole exhibits significant difference in the spatial parameters between both the Newtonian and nonNewtonians models. The comparison of local shear stress magnitude in CCA, ICA and ECA demonstrates that WSS is highly influenced by the shear thinning property of blood. This variation is also observed artery branches with reduced lumen diameter, lumen narrowing due to stenosis and in the bifurcation zone

Item Type: Article
Uncontrolled Keywords: ANSYS CFX , Carotid bifurcation artery, Newtonian and Carreau - Yasuda model, Wall shear stress
Subjects: Engineering > MIT Manipal > Mechanical and Manufacturing
Depositing User: MIT Library
Date Deposited: 06 Oct 2020 09:45
Last Modified: 06 Oct 2020 09:45
URI: http://eprints.manipal.edu/id/eprint/155740

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