Traumatic ulcerative granuloma with stromal eosinophilia (tugse)-a precursor of oral squamous cell carcinoma?

Kumar, Mathangi and Vineetha, R and Pai, Keerthilatha M and Kamath, Abhay Taranath and Chandrashekhar, Chetana Traumatic ulcerative granuloma with stromal eosinophilia (tugse)-a precursor of oral squamous cell carcinoma? Cumhuriyet Dental Journal, 23 (1). pp. 67-70. ISSN 2146-2852

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Abstract

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign, chronic, reactive and self-healing lesion. It is composed of abundant eosinophils and small lymphocytes. Several studies have shown varying observations on the relation of tissue eosinophilia with the prognosis of oral cancer. Here, we present a case of a 65-year-old male who presented with a non-healing ulcer on the lateral border of the tongue, which was suggestive of TUGSE on histopathological examination. The patient was kept on strict monthly follow up and the second re-biopsy was suggestive of moderately differentiated squamous cell carcinoma. Literature does not support the transformation of TUGSE to oral squamous cell carcinoma; however, our experience suggests a close vigilance of such lesions due to its high clinical resemblance to malignancy. Hence, repeat biopsies on a regular basis are mandatory in cases where the clinical picture is highly suspicious

Item Type: Article
Uncontrolled Keywords: Oral cancer; Squamous cell carcinoma; Eosinophilia; Tongue cancer; Prognosis; Lymph node
Subjects: Dentistry > MCODS Manipal > Oral and Maxillofacial Surgery
Dentistry > MCODS Manipal > Oral Medicine and Radiology
Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Depositing User: KMC Library
Date Deposited: 14 Oct 2020 04:05
Last Modified: 14 Oct 2020 04:05
URI: http://eprints.manipal.edu/id/eprint/155801

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