Microbiological profile of chronicosteomyelitis with special reference to anaerobic osteomyelitis in a tertiary care hospital of coastal Karnataka

Shenoy, Padmaja A and Vishwanath, Shashidhar and Bhat, Shyamasunder N and Mukhopadhyay, Chiranjay and Chawla, Kiran (2020) Microbiological profile of chronicosteomyelitis with special reference to anaerobic osteomyelitis in a tertiary care hospital of coastal Karnataka. Tropical Doctor, 50 (3). pp. 198-202. ISSN 1758-1133

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Abstract

Chronic osteomyelitis is a relapsing, persistent, low-grade inflammation of bone caused by various infectious agents. The present study, conducted over a two-year period, on specimens received from cases of chronic osteomyelitis was, to determine the frequency of isolation of aerobic and anaerobic bacteria and to analyse their antimicrobial susceptibility pattern. Specimens were processed for Gram stain, aerobic and anaerobic culture, and were identified according to standard techniques. Significant growth was observed in 102/204 specimens, in which aerobic growth was observed in 62 (60.8%) and anaerobic in 40 (39.2%). Resistance to metronidazole and clindamycin was observed in 6.7% and 30% of the anaerobic isolates, respectively. None of these were resistant to meropenem. A significant proportion of anaerobic isolates were found to be resistant to commonly used empirical drugs, such as clindamycin, thus necessitating a need for routine anaerobic susceptibility testing.

Item Type: Article
Uncontrolled Keywords: Anaerobic osteomyelitis; microbiological profile; clindamycin; metronidazole; antimicrobial resistance.
Subjects: Medicine > KMC Manipal > Microbiology
Medicine > KMC Manipal > Orthopaedics
Depositing User: KMC Library
Date Deposited: 15 Oct 2020 04:14
Last Modified: 15 Oct 2020 04:14
URI: http://eprints.manipal.edu/id/eprint/155874

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