Cannabinoids as an Alternative Option for Conventional Analgesics in Cancer Pain Management: A Pharmacogenomics Perspective

Jose, Anmi and Thomas, Levin and Baburaj, Gayathri and Munisamy, Murali and Rao, Mahadev (2020) Cannabinoids as an Alternative Option for Conventional Analgesics in Cancer Pain Management: A Pharmacogenomics Perspective. Indian Journal of Palliative Care, 26 (1). pp. 129-133. ISSN 0973-1075

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Abstract

The global cancer burden is significantly increasing at an alarming rate affecting patients, relatives, communities, and health‑care system. Cancer patients require adequate pain relief and palliative care throughout the life course, especially in terminal illness. Although opioid treatment is successful in majority of patients, around 40% do not achieve enough analgesia or are prone to serious side effects and toxicity. The treatment of medical conditions with cannabis and cannabinoid compounds is constantly expanding. This review organizes the current knowledge in the context of SNPs associated with opioids and nonopioids and its clinical consequences in pain management and pharmacogenetic targets of cannabinoids, for use in clinical practice

Item Type: Article
Uncontrolled Keywords: Cancer pain; Cannabinoids; Nonopioids; Opioids; Pharmacogenomics
Subjects: Pharmacy > MCOPS Manipal > Pharmacy Practice
Depositing User: KMC Library
Date Deposited: 21 Oct 2020 10:30
Last Modified: 21 Oct 2020 10:30
URI: http://eprints.manipal.edu/id/eprint/155934

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