Cold en bloc excision (CEBE) of bladder tumours using Zedd excision scissors: a prospective, pilot, safety and feasibility study

Hameed, BM Zeeshan and Hegde, Padmaraj and Shah, Milap and Rai, Bhavan Prasad and Thomas, Joseph and Pai, Kanthilatha and Naik, Nithesh and Somani, Bhaskar K (2020) Cold en bloc excision (CEBE) of bladder tumours using Zedd excision scissors: a prospective, pilot, safety and feasibility study. Therapeutic Advances in Urology, 12. pp. 1-7. ISSN 1756-2872

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Background: Transurethral resection of bladder tumour (TURBT) is the traditional technique of choice for endoscopically suspected bladder tumours. Cold En Bloc Excision (CEBE) using novel Zedd scissors is proposed for endoscopic treatment of patients with non-muscle invasive bladder cancer (NMIBC). The aim of this study was to evaluate feasibility and safety of CEBE of bladder tumours using Zedd scissors. Methods: A pilot prospective study of patients who underwent a CEBE of suspicious bladder tumours using Zedd scissors was conducted. A total of 23 patients underwent CEBE for suspected bladder tumours using Zedd scissors. New and recurrent tumours <3cm were included in the study. The outcome measures were the presence of detrusor muscle (DM) and obturator nerve reflex (ONR), bladder perforation rates, specimen cautery artefacts, recurrence rates and complication rates. The mean age was 64years±10.41 (range: 49– 83years). The median follow up was 4months (range 1–9months). The mean tumour size was 1.8cm±0.40 (range: 0.8–2.6cm). Tumours were located in the lateral wall (n=11), dome (n=2), posterior wall (n=6), trigone (n=2), anterior wall (n=4) and the junction of lateral and posterior wall (n=4). Results: There was no ONR or bladder perforation and none of the patients had any complications. DM was present in 21 patients (91%). There was no tumour identified at the circumferential margins. There was no cautery artefact reported in any case. No patients had a recurrence at first follow up cystoscopy and two patients had out of field recurrence at subsequent cystoscopies. Conclusion: CEBE with Zedd scissors is a promising en bloc excision technique for bladder tumour. It is a safe and feasible for excision of tumours less than 3cm. The early oncological outcomes are comparable with existing en bloc resection techniques (ERBT) for NMIBC.

Item Type: Article
Uncontrolled Keywords: bladder cancer, bladder tumours, cold en bloc excision, non-muscle-invasive bladder cancer, urothelial cancer, Zedd scissors
Subjects: Engineering > MIT Manipal > Mechanical and Manufacturing
Depositing User: MIT Library
Date Deposited: 01 Jan 2021 04:32
Last Modified: 01 Jan 2021 04:32

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