Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery

Dsouza, Leonna and Ghate, Vivek M and Lewis, Shaila Angela (2020) Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery. Biomedical Microdevices, 22 (77). pp. 1-11. ISSN 1387-2176

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Abstract

Derma roller, a device rolled onto the skin to form micropores, is extensively used for cosmetic purposes. The pores thus created are utilized to either result in the induction of collagen production, leading to glowing and wrinkle-free skin or for permeating the applied formulations to the site of action within the skin. Recent studies have shown the benefits of using derma rollers for transdermal delivery of drugs. In the nascent stage, this approach paves a way to successfully breach the stratum corneum and aid in the movement of medications directed towards the dermis and the hair follicles. The review essentially summarizes the evidence of the use of derma rollers in cosmetic setup, their designing, and the preclinical and clinical reports of efficacy, safety, and concerns when translated for pharmaceutical purposes and transdermal drug delivery.

Item Type: Article
Uncontrolled Keywords: Derma rollers ; Micro-needling ; Cosmetics ; Transdermal drug delivery ; Skin ; Micropores.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 27 Jan 2021 11:59
Last Modified: 27 Jan 2021 11:59
URI: http://eprints.manipal.edu/id/eprint/156353

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