Surface engineered bimetallic nanoparticles based therapeutic and imaging platform: recent advancements and future perspective

Kotha, Rohini and Fernandes, Gasper and Nikam, Ajinkya Nitin and Kulkarni, Sanjay and Pandey, Abhijeet and Mutalik, Srinivas (2020) Surface engineered bimetallic nanoparticles based therapeutic and imaging platform: recent advancements and future perspective. Materials Science And Technology, 36 (16). pp. 1729-1748. ISSN 0267-0836

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Abstract

The unique physical and chemical properties of monometallic nanoparticles have been comprehensively explored. Analogously, the combination of two metals induces alterations in the system’s electron density, termed as Bimetallic nanoparticles (BMNP’s) were found to be more desirable than monometallic nanoparticles due to improved stability, activity, and selectivity, thus altering the chemical, optical, and electrical properties. In this review, we showcase the importance in the context of biomedical applications. The article sheds light on utilising BMNP’s in the field of theranostics, diagnosis, and therapeutics by focusing on anticancer, antimicrobial and wound healing activity along with the toxicological problems associated with BMNP’s. In conclusion, BMNP’s can be used as a novel therapeutic and diagnostic system to tackle major health concerns.

Item Type: Article
Uncontrolled Keywords: Bimetallic nanoparticles; sputtering; thermal decomposition; toxicity; safety.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Research > Research Center - Health Sciences
Depositing User: KMC Library
Date Deposited: 12 Mar 2021 07:02
Last Modified: 12 Mar 2021 07:02
URI: http://eprints.manipal.edu/id/eprint/156459

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