Validation of Segmented Brain Tumor from MRI Images Using 3D Printing

Nayak, Ujwal Ashok and Balachandra, Mamatha and Manjunath, K N and Kurady, Rajendra (2021) Validation of Segmented Brain Tumor from MRI Images Using 3D Printing. Asian Pacific Journal of Cancer Prevention. pp. 523-530. ISSN 1513-7368

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Early diagnosis of a brain tumor is important for improving the treatment possibilities. Manually segmenting the tumor from the volumetric data is time-consuming, and the visualization of the tumor is rather challenging. Methods: This paper proposes a user-guided brain tumour segmentation from MRI (Magnetic Resonance Imaging) images developed using Medical Imaging Interaction Toolkit (MITK) and printing the segmented object using the 3D printer for tumour quantification. The proposed method includes segmenting the tumour interactively using connected threshold method, then printing the physical object from the segmented volume of interest. Then the distance between two voxels was measured using electronic callipers on the 3D volume in a specific direction. And next, the same distance was measured in the same direction on the 3D printed object. Results: The technique was tested with n=5 samples (20 readings) of brain MRI images from RIDER Neuro MRI dataset of National Cancer Institute. MITK provides various tools that enable image visualization, registration, and contouring. We were able to achieve the same measurements using both the approaches and this has been tested statistically with paired t-test method. Through this and the observer’s opinion, the accuracy of the segmentation was proved. Conclusion: When the difference in measurement of tumor volume through the electronic calipers and with 3D printed object equates to zero, proves that the segmentation technique is accurate. This helps to delineate the tumor more accurately during radio therapy.

Item Type: Article
Uncontrolled Keywords: Medical image analysis- image processing- image segmentation- 3D printing
Subjects: Engineering > MIT Manipal > Computer Science and Engineering
Depositing User: MIT Library
Date Deposited: 05 Apr 2021 09:36
Last Modified: 05 Apr 2021 09:36

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