Remineralization potential of theobromine on artificial carious lesions

Taneja, Vani and Nekkanti, Sridhar and Gupta, Kanishk (2019) Remineralization potential of theobromine on artificial carious lesions. Journal of International Society of Preventive and Community Dentistry, 9 (6). pp. 576-583. ISSN 2231-0762

[img] PDF
RMS - 00009796.pdf - Published Version
Restricted to Registered users only

Download (682kB) | Request a copy


Background and Aims: This study aimed to investigate the remineralization potential of two concentrations of theobromine (100mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis. Materials and Methods: Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (ColgateTM, Colgate –Palmolive, India), Novamine- Shy NMTM, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin ProTM, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classicTM, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX. Results: A Tukey post-hoc test revealed statistically significant difference between NovaMin and all the other toothpastes (P < 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found. Conclusion: Theobromine can be used as an effective novel remineralizing agent alternative to the already available agents.

Item Type: Article
Uncontrolled Keywords: Nanohydroxyapatite; NovaMin; remineralization; theobromine.
Subjects: Dentistry > MCODS Manipal > Pedodontics and preventive Dentistry
Depositing User: KMC Library
Date Deposited: 01 Jul 2021 10:06
Last Modified: 01 Jul 2021 10:06

Actions (login required)

View Item View Item