Structurally nanoengineered antimicrobial peptide polymers: design,synthesis and biomedical applications

Ramamurthy, Ronisha and Mehta, Chetan H and Nayak, Usha Y (2021) Structurally nanoengineered antimicrobial peptide polymers: design,synthesis and biomedical applications. World Journal of Microbiology and Biotechnology, 37. pp. 1-13. ISSN 0959-3993

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Abstract

Antimicrobial resistance not only increases the contagiousness of infectious diseases but also a threat for the future as it is one of the health care concern around the globe. Conventional antibiotics are unsuccessful in combating chronic infections caused by multidrug-resistant (MDR) bacteria, therefore it is important to design and develop novel strategies to tackle this problems. Among various novel strategies, Structurally Nanoengineered Antimicrobial Peptide Polymers (SNAPPs) have been introduced in recent years to overcome this global health care issue and they are found to be more efficient in their performance. Many facile methods are adapted to synthesize complex SNAPPs with required dimensions and unique functionalities. Their unique characteristics and remarkable properties have been exploited for their immense applications in various fields including biomedicine, targeting therapies, gene delivery, bioimaging, and many more. This review article deals with its background, design, synthesis, mechanism of action, and wider applications in various fields of SNAPPs

Item Type: Article
Uncontrolled Keywords: Antimicrobial resistance; Bio-imaging; Drug delivery; Reversible addition fragmentation chain transfer (RAFT; Ring-opening polymerization (ROP); Structurally nano engineered antimicrobial peptide polymers (SNAPPs)
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 08 Sep 2021 10:32
Last Modified: 08 Sep 2021 10:32
URI: http://eprints.manipal.edu/id/eprint/157296

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