Advances in mitochondrial medicine and translational research

Kuthethur, Raviprasad and Prasad, Keshava and Chakrabarty, Sanjiban and Kabekkodu, Shama Prasada and Satyamoorthy, K (2021) Advances in mitochondrial medicine and translational research. Mitochondrion, 61. pp. 62-68. ISSN 1567-7249

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Abstract

Current knowledge of mitochondrial biology and function has provided tools and technologies that helped a better understanding of the molecular etiology of complex mitochondrial disorders. Dual genetic control of this subcellular organelle function regulates various signaling mechanisms which are essential for metabolism, bioenergetics, fatty acid biosynthesis, and DNA replication & repair. Understanding nuclear mitochondrial crosstalk through advanced genomics as well as clinical perspectives is the overall basis of mitochondrial research and medicine, also the sole objective of Society for Mitochondrial Medicine and Research (SMRM) - India. The eighth virtual international conference on ‘Advances in Mitochondrial Medicine and Translational Research’ was organized at the Manipal School of Life Sciences, MAHE, Manipal, India, during 6 – 7 November 2020. The aim of the virtual conference was to highlight the recent advances and future perspectives that represent comprehensive clinical and fundamental research interests in the area of mitochondrial biology of human diseases. To systematically present the various findings in mitochondrial biology, the meeting was themed with specific aspects comprising (a) mitochondrial disorders: clinical & genomic perspectives, (b) mitochondria in cancer, (c) mitochondrial metabolism & disorders, and (d) mitochondrial diseases & therapy. This report provides an overview of the recent advancements in the area of mitochondrial biology and medicine that was discussed at the conference.

Item Type: Article
Uncontrolled Keywords: Mitochondrial disorders ; Mitochondrial metabolism; Anterograde and retrograde signaling; Cancer and mitochondria; miRNAs and mitochondria ; Therapeutics and mitochondria.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Library
Date Deposited: 27 Nov 2021 05:59
Last Modified: 27 Nov 2021 05:59
URI: http://eprints.manipal.edu/id/eprint/157774

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