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Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers

Karemore, Gopal and Sujatha, * and Rai, Lavanya and Pai, Keerthilatha M and Kartha, VB and Santhosh, C (2009) Performance Liquid Chromatography-Laser Induced Fluorescence: Case of Cervical and Oral Cancers. Proc. of SPIE.

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Abstract

The serum protein profiles of normal subjects, patients diagnosed with cervical cancer, and oral cancer were recorded using High Performance Liquid Chromatography combined with Laser Induced Fluorescence detection (HPLC-LIF). Serum protein profiles of the above three classes were tested for establishing the ability of HPLC-LIF protein profiling technique for discrimination, using hard clustering and Fuzzy clustering methods. The clustering algorithms have quite successfully classified the profiles as belonging to normal, cancer of cervix, and oral cancer conditions.

Item Type: Article
Uncontrolled Keywords: Serum Protein Profile, HPLC-LIF, Clustering Algorithms, Cancer Diagnosis, Oral cancer
Subjects: Dentistry > MCODS Manipal > Oral Medicine and Radiology
Departments at MU > Atomic Molecular Physics
Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Manipal
Date Deposited: 24 Oct 2011 09:54
Last Modified: 08 Feb 2013 09:54
URI: http://eprints.manipal.edu/id/eprint/1579

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