Liposomes as Versatile Platform for Cancer Theranostics: Therapy, Bio-imaging, and Toxicological Aspects

Mehta, Swapnil and Kulkarni, Sanjay and Nikam, Ajinkya N and Padya, Bharat S and Pandey, Abhijeet and Mutalik, Srinivas (2021) Liposomes as Versatile Platform for Cancer Theranostics: Therapy, Bio-imaging, and Toxicological Aspects. Current Pharmaceutical Design, 27 (17). pp. 1977-1991. ISSN 1381-6128

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Abstract

Liposomes are nano-sized formulations having the benefits of site-specificity, biocompatibility, and biodegradability, which make them useful for the therapy and diagnosis of major diseases like cancer. In this review, various synthetic strategies of liposomes and their biomedical application in special concern to cancer are discussed. In context to the biomedical application, this article gives a detailed insight into subcellular targeted therapy and several therapeutic modifications like immunotherapy, receptor-based therapy, phototherapy, and combination therapy. The review also describes the liposome-based imaging platforms and the toxicity associated with liposomes. Owing to a significant amount of benefits of this carrier system, several products have been approved to be launched in the market and several others have already been marketed for clinical use

Item Type: Article
Uncontrolled Keywords: Liposomes; Cancer therapy; Imaging platform; Site-specificity; Toxicity; Toxicological aspects
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 28 Jan 2022 04:21
Last Modified: 28 Jan 2022 04:21
URI: http://eprints.manipal.edu/id/eprint/158057

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