Kamath, Saritha U and Rakshith, * (2020) Effects of prebiotics, probiotics intervention in children with autism spectrum disorder – A systematic review. Biomedicine, 40 (2). pp. 119-122. ISSN 0970-2067

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Abstract

Gastrointestinal (GI) microbiota is one of the determining factors in handling the neuronal and psychological features in Autism spectrum disorder (ASD) and corrected by restoring the microbiome environment by the supplementation of pre and probiotics. Purpose of this article is to draw evidence by systematic review for the effects of prebiotics, probiotics intervention in children with an autism spectrum disorder. Selected data sources were searched for relevant literature and included as per the set criteria from January 2019 to August 2019 by two authors and the third author resolved discrepancy. Finally, 4 articles were selected for the in-depth review as per the format by considering inclusion and exclusion. Probiotics and prebiotics have shown good effects in improving some of the symptoms of autism spectrum disorder. However, available evidence is limited. More studies are required to obtain a better conclusion in this area by increasing the sample size

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