Oral lesions containing amyloid-like material

Radhakrishnan, Raghu (2021) Oral lesions containing amyloid-like material. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 132 (2). pp. 190-201. ISSN 2212-4403

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During oral pathology daily practice, true amyloid may be identified in oral amyloidosis and several odontogenic tumors. However, histologic examination often reveals other oral and perioral diseases with similar eosinophilic, acellular, amorphous substances. These include extensive areas of collagenous sclerosis, fibrin deposition, elastic fiber degeneration, and dentinoid material, which may resemble amyloid under light microscopic examination. These materials are often termed “amyloid-like” due to their close histologic resemblance to true amyloid. The rarity of most of these conditions and their strong histologic similarity may hamper an accurate diagnosis. Definitive diagnosis of these lesions may require clinical correlation; laboratory evaluation; histochemical or immunohistochemical reactions; and, in some cases, genetic investigation. In this review, we describe the main clinicopathologic features of this group of diseases that may manifest in the oral and/or perioral regions and that have in common the presence of amyloid-like material deposition

Item Type: Article
Subjects: Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Depositing User: KMC Library
Date Deposited: 01 Feb 2022 10:49
Last Modified: 01 Feb 2022 10:49
URI: http://eprints.manipal.edu/id/eprint/158260

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