Paper and thread as media for the frugal detection of urinary tract infections (UTIs)

Hasandka, Amrutha and Singh, Ankita Ramchandran and Prabhu, Anusha and Singhal, Hardik Ramesh and Nandagopal, Giri M S and Mani, Naresh Kumar (2022) Paper and thread as media for the frugal detection of urinary tract infections (UTIs). Analytical and Bioanalytical Chemistry, 41. pp. 847-865. ISSN 1618-2642

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Abstract

Urinary tract infections (UTIs) make up a significant proportion of the global burden of disease in vulnerable groups and tend to substantially impair the quality of life of those affected, making timely detection of UTIs a priority for public health. However, economic and societal barriers drastically reduce accessibility of traditional lab-based testing methods for critical patient groups in low-resource areas, negatively affecting their overall healthcare outcomes. As a result, cellulose-based materials such as paper and thread have garnered significant interest among researchers as substrates for so-called frugal analytical devices which leverage the material’s portability and adaptability for facile and reproducible diagnoses of UTIs. Although the field may be only in its infancy, strategies aimed at commercial penetration can appreciably increase access to more healthcare options for at�risk people. In this review, we catalogue recent advances in devices that use cellulose-based materials as the primary housing or medium for UTI detection and chart out trends in the field. We also explore different modalities employed for detection, with particular emphasis on their ability to be ported onto discreet casings such as sanitary products

Item Type: Article
Uncontrolled Keywords: Urinary tract infection . Detection . Paper . Thread . Microfluidics
Subjects: Engineering > MIT Manipal > Biotechnology
Engineering > MIT Manipal > Chemical
Depositing User: MIT Library
Date Deposited: 03 Mar 2022 06:05
Last Modified: 03 Mar 2022 06:05
URI: http://eprints.manipal.edu/id/eprint/158328

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