A new microwave-assisted method for the synthesis of 2-substituted-thiazol-4(5h)-one via hantzsch condensation

Nayak, Swarnagowri and Gaonkar, Santosh L (2022) A new microwave-assisted method for the synthesis of 2-substituted-thiazol-4(5h)-one via hantzsch condensation. Rasayan Journal of Chemistry, 15 (1). pp. 310-315. ISSN 0974-1496

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Abstract

A new microwave-assisted method is developed for the synthesis of 2-substituted-thiazol-4(5H)-ones via Hantzsch condensation by a simple experimental protocol without using any catalyst. The products were isolated in excellent yield without any purification. Synthesized compounds were characterized by applying FTIR, 1H NMR, 13C NMR, and mass spectral studies and a plausible mechanism is proposed for the formation of the product. The method is versatile for the preparation of a new class of 2-substituted-thiazol-4(5H)-ones

Item Type: Article
Uncontrolled Keywords: Microwave Heating, 2-substituted-thiazol-4(5H)-one, Hantzsch Condensation, Cyclocondensation.
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 23 Jun 2022 10:30
Last Modified: 23 Jun 2022 10:30
URI: http://eprints.manipal.edu/id/eprint/158883

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