Effect of betamethasone valerate with biopolymer on skin inflammatory models In albino mice and wistar rats

Satish Kumar, MC and Adiga, Sachidananda and D’Souza, Avin and Sirigiri, Purnima and Ayappa, Deepa and Nayak, Veena and Chogtu, Bharti and Bairy, KL (2010) Effect of betamethasone valerate with biopolymer on skin inflammatory models In albino mice and wistar rats. International Journal of Pharmaceutical Sciences Review and Research, 4 (2). pp. 173-175.

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Abstract

There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based betamethasone valerate. This study was done to compare the efficacy of betamethasone valerate with neomycin (Betnovate N) with betamethasone valerate with biopolymer in animal models of superficial skin inflammation in rats and mice. The inflammatory models croton oil ear edema in rats and topical application of arachadonic acid in mice were used. In both the models, the animals treated with betamethasone valerate with biopolymer showed a significant decrease in inflammation as compared to Betnovate N group.

Item Type: Article
Uncontrolled Keywords: Inflammation, betamethasone valerate with biopolymer.
Subjects: Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 24 Nov 2011 10:44
Last Modified: 24 Nov 2011 10:44
URI: http://eprints.manipal.edu/id/eprint/1770

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