Oxidative stress in children with endemic skeletal fluorosis

Shivarajashankara, YM and Shivashankara, AR and Rao, Hanumanth S and Bhat, Gopalakrishna P (2001) Oxidative stress in children with endemic skeletal fluorosis. Fluoride , 34 (2). pp. 103-107.

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Abstract

In the village of Kheru Nayak Thanda in the Gulbarga district of Karnataka, India, 18 children aged 3 to 10 years with endemic skeletal fluorosis were shown to have oxidative stress as evidenced by elevated levels of malondialdehyde in their red blood cells, indicating increased lipid peroxidation. Significant alterations of antioxidant systems in the blood were confirmed by decreased levels of glutathione and uric acid together with an increase in the activity of glutathione peroxidase as well as the level of ascorbic acid along with a slight decrease in the activity of superoxide dismutase.

Item Type: Article
Uncontrolled Keywords: Antioxidants, Ascorbic acid, Glutathione levels, Glutathione peroxidase, Gulbarga district, Karnataka, India, Kheru Nayak Thanda, Lipid peroxidation, Malondialdehyde levels, Skeletal fluorosis, Superoxide dismutase
Subjects: Medicine > KMC Manipal > Biochemistry
Depositing User: KMC Manipal
Date Deposited: 13 Dec 2011 04:36
Last Modified: 13 Dec 2011 04:36
URI: http://eprints.manipal.edu/id/eprint/1792

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