A Novel Anti-Oxidant Lemon grass Oil MouthWash-a clinical trial

Meena Anand, K and Goyal, Ruchika and Bhat, Subraya G and Kamath, Shobha and Aggarwal, Madhur and Bhandarkar, Meghna A and Mahima, BS and Sukreeth, Sonal (2011) A Novel Anti-Oxidant Lemon grass Oil MouthWash-a clinical trial. ASIAN J. EXP. BIOL. SCI, 2 (3).

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Abstract

Natural antioxidants are presumed to be safe since they occur in plant foods, and are seen as more desirable than their synthetic counter parts. Plants also possess enzymatic systems that protect them against H2O2 and other harmful reactive oxygen species; these include superoxide dismutase (SOD) and catalase. Antioxidants are those substances which when present in minimum quantities prevents the oxidation of a substrate. Recently, there has been a considerable interest in finding natural antioxidants fromplants The aim of our study was to compare the efficacy of lemongrass oil mouthwash for anti oxidant property by estimation of superoxide dismutase levels before and after administration of lemongrass oil mouthwash.Atotal of 40 subjects were included in this study. Subjects were divided into 4 groups i.e. 3 test groups and one control group. Initially, saliva and gingival crevicular fluid (GCF) were collected and sent for analyzing the antioxidant level levels.Lemongrass oil mouthwash was administered at three different concentrations and estimation of antioxidants was done after 15 days by collecting saliva and gingival crevicular fluid. The subjects in the case group showed increased antioxidant levels when compared to the control group. There was no statistical difference in the antioxidant levels within the case groups. The lemongrass oil mouthwash was found to have anti oxidant activity at all the three concentrations levels.

Item Type: Article
Subjects: Medicine > KMC Manipal > Biochemistry
Dentistry > MCODS Manipal > Periodontology
Depositing User: KMC Manipal
Date Deposited: 15 Dec 2011 09:15
Last Modified: 15 Dec 2011 09:15
URI: http://eprints.manipal.edu/id/eprint/1814

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