Leukocyte count on admission as a predictor of clinical outcome in the expectant management for women with preterm prelabor rupture of membranes

Pandey, Deeksha and Bhagat, Saurav and Vanya, Vidhi and Binu, VS and Pai, Muralidhar and Kumar, Pratap (2011) Leukocyte count on admission as a predictor of clinical outcome in the expectant management for women with preterm prelabor rupture of membranes. Sri Lanka Journal of Obstetrics and Gynaecology, 33. pp. 51-55.

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Abstract

Objective: We hypothesized that a single value of leukocyte count, on admission might be a helpful predictor to prognosticate the clinical outcome and plan the management (early delivery versus conservative management) in patients presenting with pre term pre-labour rupture of membranes (PPROM). Design: Observational study. Setting: This study was conducted in a tertiary care centre. Population or sample: 127 pregnancies complicated with PPROM. Method: A novel scoring system was devised depending upon the final clinical performance. Main outcome measure: Adverse fetal, neonatal and maternal outcome. Result: Based on the score cut off for the total leukocyte count was calculated to prognosticate the outcome. Leukocyte count of 15,850/mm3, at the time of admission was found to be able to predict the clinical outcome with a sensitivity of 85.7% and specificity of 87.6%, in a case of PPROM. Whereas the individual components of differential leukocyte counts were found to be not of much help in this regard. Conclusion: Leukocyte count of 15,850/mm3 at admission can be used to prognosticate outcome in pregnancies complicated with PPROM.

Item Type: Article
Uncontrolled Keywords: Preterm prelabor rupture of membranes, Total leukocyte count, Differential count, Prematurity, Infectious morbidity.
Subjects: Departments at MU > Statistics
Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Manipal
Date Deposited: 03 Jan 2012 06:54
Last Modified: 03 Jan 2012 06:54
URI: http://eprints.manipal.edu/id/eprint/2176

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