Predictive Control of Blood Glucose Concentration in Type I Diabetic Patients

Kamath, Surekha and George, V I and Vidyasagar, Sudha (2008) Predictive Control of Blood Glucose Concentration in Type I Diabetic Patients. ICGST-BIME Journal, 8 (1). pp. 39-43. ISSN 1687-482X

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Maintaining the glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H∞ control is applied for the insulin delivery to prevent the hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several patients is used as reference model.Simulation studies are performed on the diabetic patient model under feedback control, which revealed that the proposed control strategy is able to control the blood glucose concentration well within the acceptable limits and also able to compensate for the slow parametric drifts.

Item Type: Article
Uncontrolled Keywords: IDDM, insulin modeling, Glucose insulin modeling, mathematical modeling, H∞ control, Robust control.
Subjects: Engineering > MIT Manipal > Instrumentation and Control
Depositing User: MIT Library
Date Deposited: 12 Jan 2012 11:09
Last Modified: 15 Jan 2014 10:21

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