Kamath, Surekha and George, V I and Vidyasagar, Sudha (2009) Closed loop Control Strategy for Blood Glucose Regulation System. International Journal of Chemical Engineering Research, 1 (1). pp. 21-29. ISSN 0975 - 6442

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Abstract

Maintaining the glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H∞ control is applied for the insulin delivery to prevent the hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several patients is used as reference model. Simulation studies are performed on the diabetic patient model under feedback control, which revealed that the proposed control strategy is able to control the blood glucose concentration well within the acceptable limits and also able to compensate for the slow parametric drifts.

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