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Urinary excretion of biogenic amine metabolites in migraine

Rao, A and Rao, SN (1988) Urinary excretion of biogenic amine metabolites in migraine. Biochemical Archives, 4. pp. 141-144.

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Abstract

Urinary total catecholamines, their metabolites and5-hydroxy indols acetic acid which is a metabolite of serotonin have been investigated in 25 patients with migraine and in 20 controls.the levels of total cate-cholamine, vanillic mandalic acid and 3- methoxy-4 hydroxy phenyl glycol were not significantly different from the controls.However,the mean 5-hydroxy indole acetic acid excretion in case of migraine was significantly decreased associated with a significant increase in the mean hornovanillice acid,17- hydroxy corticosteroids excretion as dornpared to the control group.it is concluded that a dopaminergic and a serotonergic disturbanced is involvod in the pathogenesis of migraine.

Item Type: Article
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Neurology
Depositing User: KMC Manipal
Date Deposited: 20 Jan 2012 06:05
Last Modified: 20 Jan 2012 06:05
URI: http://eprints.manipal.edu/id/eprint/2542

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