Plasma protein oxidation and total antioxident powver in premenstrual syndrome

Tuladhar, Earn Tara and Rao, Anjali (2010) Plasma protein oxidation and total antioxident powver in premenstrual syndrome. Asian Pacific Journal of Tropical Medicine, 3 (3). pp. 237-240.

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Abstract

Objective To explore whether oxidative stress has any role in premenstrual syndrome (PMS).Methods Female volunteers suffering from PMS,in the age group of 20–24 years were compared to their asymptomatic normomennorhoeic counterparts in follicular phase and late luteal phase for ferric reducing antioxidant power of plasma (FRAP), plasma protein thiols (PPT) and protein carbonyls (PPC) levels Results there was no significant change in FRAP and PPC levels in controls and PMS groups but PPT decreased significantly in luteal phase of PMS (P<0.05) when compared to follicular phase.Conclusions Estrogen and progesterone, might be responsible for a healthy antioxidant profile in PMS.However, a marked decrease in PPT in luteal phase of PMS group may be due to pro-oxidant nature of estrogen-active in this phase of PMS leading to consumption of the sacrificial antioxidant-protein thiol.

Item Type: Article
Uncontrolled Keywords: Ferric reducing antioxidant power of; plasma; Premenstrual tension; Protein thiol; Protein carbonyl
Subjects: Medicine > KMC Manipal > Biochemistry
Depositing User: KMC Manipal
Date Deposited: 16 Jan 2012 09:55
Last Modified: 16 Jan 2012 09:55
URI: http://eprints.manipal.edu/id/eprint/2550

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