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Neuropharmacological activity of Acorus calamus

Martis, G and Rao, A and Karanth, KS (1991) Neuropharmacological activity of Acorus calamus. FITOTERAPIA , 42 (4). pp. 331-336.

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Abstract

The aqueous and alcoholic extracts of A,calamus reduced the severity of maximum electric shock induced seizures in rats but did not exhibit complete protection. Further, the extracts significantly increased the pentylenetetrazole induced seizure latency. the extracts did not exhibit any antidepressant or sedative effects nor produce muscle incoordination. Howerver, both the extracts potentiated the barbiturate induced hypnosis. Thus, administration of the extraacts for longer duration in combination with reduced doses of standard drug used for treating "petit mal" epilepsy may probe to be beneficial in these patients.

Item Type: Article
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 19 Jan 2012 06:22
Last Modified: 19 Jan 2012 06:22
URI: http://eprints.manipal.edu/id/eprint/2572

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