Neuropharmacological activity of withania somnifera

Prabhu, Vidya M and Rao, A and Karanth, KS (1990) Neuropharmacological activity of withania somnifera. Fitoterapia , 61 (3). pp. 237-240.

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The Alcoholic extract of the root of W, somnifera did not protect the animals from chemically or MES induced seizures. The extract neither produced muscle incoordination nor have an antidepressant effect in lower doses. It did not produce an effective sedation also. However, it potentiated the barbiturate induced hypnosis. The extract significantly increased the pentylenetetrazole induced seizure latency. Therefore, probably the administration of the extract for longer duration may havea beneficial effect in petitmal epilepsy

Item Type: Article
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 19 Jan 2012 06:16
Last Modified: 19 Jan 2012 06:16

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