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Wound healing profile of Sauropus androgynous in wistar rats

*, Aruna Bhaskar and *, K.V.Ramesh and *, Rajeshwari (2009) Wound healing profile of Sauropus androgynous in wistar rats. Journal of Natural Remedies, 9 (2). pp. 159-164.

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Abstract

Objective: To evaluate the effect of Sauropus androgynous on wound healing. Materials and methods: Excision and incision wound models were used to evaluate the wound healing activity of 5% Sauropus androgynous on wistar rats of either sex. Results: Sauropus androgynousextract promoted the wound healing activity significantly in both wound models studied, while no action was seen with ointment base. It augmented wound contraction significantly (P<0.001), re-epithelization very significantly (P<0.0001) and increase in wound breaking strength (P<0.001). Histological evaluation of wound tissue showed abundant collegenation, fibroblast and lesser macrophages in animal treated with 5% Sauropus androgynous when compared to control and ointment base. Conclusion: Extract of Sauropus androgynouspromotes wound healing activity.

Item Type: Article
Uncontrolled Keywords: Sauropus androgynous, wound healing, wound re-epithelization, wound contration
Subjects: Medicine > KMC Mangalore > Pharmacology
Depositing User: KMCMLR User
Date Deposited: 16 Jan 2012 09:36
Last Modified: 16 Jan 2012 09:36
URI: http://eprints.manipal.edu/id/eprint/2612

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