Protection of cyclophosphamide induced myelosuppression alcoholic extract of pimenta dioica Yogendra Nayak and Abhilash D

Nayak, Yogendra and Abhilash, D (2008) Protection of cyclophosphamide induced myelosuppression alcoholic extract of pimenta dioica Yogendra Nayak and Abhilash D. Pharmacologyonline, 3. pp. 719-723.

[img] PDF
94._Pharmacologyonline_3,_719-723_(2008).pdf - Published Version
Restricted to Registered users only

Download (174kB) | Request a copy

Abstract

The leaves of Pimenta dioica (L) Merril (Fam: Myrtaceae) were used as medicine for pain, arthritis, fever and stress in the folklore medicine at Kerala and Mangalore. The berries are commonly known as Allspice in culinary natives of Kerala and Mangalore. The high total phenolic content in the berries and leaves were reported for antioxidant activity. In the present study we tried the alcoholic extract of leaves for protection in cyclophospamide induced myelosuppression in Swiss mice. The oral doses (250, 500, 750 mg/kg/day) showed statistically significant protection of myelosuppression.

Item Type: Article
Uncontrolled Keywords: Allspice,Pimenta dioica,Mylosuppression, Antioxidant
Subjects: Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 19 Jan 2012 09:33
Last Modified: 19 Jan 2012 09:33
URI: http://eprints.manipal.edu/id/eprint/2614

Actions (login required)

View Item View Item