Growth promoting potential of Ficus bengalensis root extracts in immature female rats

Nidhiya, ISR and Pai, KSR and Rao, Mallikarjuna C (2009) Growth promoting potential of Ficus bengalensis root extracts in immature female rats. Pharmaceutical Biology, 47 (4). pp. 268-273. ISSN 1388-0209

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Abstract

The growth promoting potential of alcohol and aqueous extracts of young prop roots of Ficus bengalensis Linn. (Moraceae), a medicinal plant widely used among the tribes of the western zone of Maharashtra state, India to increase height, was studied. Its growth promoting effect was evaluated in one-month-old immature female rats. Extracts were administered to young rats for 30 days. Significant (p < 0.05) increase in body weight was observed in alcohol and aqueous extract treated immature female rats. Animals treated with alcohol extract showed statistically significant difference (p < 0.05) in parameters such as mean food consumption, total body length and increase in alkaline phosphatase levels, a biochemical marker for bone formation. Significant results were not observed in other parameters such as feed efficiency, tail length, relative organ weight, bone density, tibial epiphyseal cartilage width and bone hydroxy proline levels. The results obtained establish the efficacy of the plant material as well as importance of chronic studies to justify the use of this plant in growth promotion.

Item Type: Article
Uncontrolled Keywords: Growth promotion; Ficus bengalensis; prop roots; Moraceae
Subjects: Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 24 Jan 2012 09:31
Last Modified: 24 Jan 2012 09:31
URI: http://eprints.manipal.edu/id/eprint/2698

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