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Evaluation of anti-inflammatory activity of aqueous and ethanolic extracts of acampe praemorsa on carrageenan-induced paw oedema in rats

Bhattacharya, Shoumyo and Bankar, Girish R and Nayak, Pawan G and Shirwaikar, Annie (2009) Evaluation of anti-inflammatory activity of aqueous and ethanolic extracts of acampe praemorsa on carrageenan-induced paw oedema in rats. Pharmacologyonline, 2. pp. 315-319.

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Abstract

The anti-inflammatory effect of the aqueous (AEAP) and ethanolic (EEAP) extracts of Acampe praemorsa were evaluated using the carrageenan-induced rat paw oedema model. AEAP exhibited significant anti-inflammatory effect at a dose of 300 mg/kg. Maximum inhibition of 48.1 % for AEAP and 11.4 % for EEAP was observed after 3 h of drug treatment, whilst the standard drugdiclofenac, produced 63.0 % of inhibition. The present study reveals that the aqueous extract of A. praemorsa is endowed with significant anti-inflammatory activity.

Item Type: Article
Uncontrolled Keywords: Acampe praemorsa, inflammation, carrageenan, paw oedema.
Subjects: Pharmacy > MCOPS Manipal > Pharmacognosy
Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 27 Jan 2012 10:15
Last Modified: 27 Jan 2012 10:15
URI: http://eprints.manipal.edu/id/eprint/2720

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