Antioxidant and antibacterial activity of new 3- methylflavones

Jayashree, BS and Alam, Afroze and Vijay Kumar, D and Nayak, Yogendra (2010) Antioxidant and antibacterial activity of new 3- methylflavones. Indian Journal of Heterocyclic Chemistry, 19 (3). pp. 237-240. ISSN 0971-1627

[img] PDF
128._Indian_Journal_of_Heterocyclic_Chemistry,Jan-March,_2010,_Vol_19,__237-240.pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy

Abstract

Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F- 4,9,11 ,12 and 20 exhibited DPPH radical scavenging activity with IC50 below 100 Ilg/ml. The same test compounds exhibited Gram positive bacterial growth inhibition in the range between 50- 100% against standard amoxicillin.

Item Type: Article
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 30 Jan 2012 06:41
Last Modified: 30 Jan 2012 06:41
URI: http://eprints.manipal.edu/id/eprint/2742

Actions (login required)

View Item View Item