Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity

Porwal, Brajesh and Jayashree, BS and Attimarad, Mahesh (2010) Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity. Journal of Basic and Clinical Pharmacy, 1 (1). pp. 29-32.

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Abstract

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl esters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). The structures of the final compounds were established by their spectral data. The antimicrobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity

Item Type: Article
Uncontrolled Keywords: Coumarins,Antimicrobial Activity
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 30 Jan 2012 10:12
Last Modified: 30 Jan 2012 10:12
URI: http://eprints.manipal.edu/id/eprint/2754

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