Synthesis and Crystal Structure of1-(2-hydroxy-4 methoxyphenyl)-3-(3-methylthiophen-2-yl) prop-en-1-one

Thippeswamy, GB and Vijay Kumar, D and Mahadeva Prasad, TN and Jayashree, BS and Sridhar, MA and Shashidhara Prasad, J (2011) Synthesis and Crystal Structure of1-(2-hydroxy-4 methoxyphenyl)-3-(3-methylthiophen-2-yl) prop-en-1-one. Structural Chemistry Communications, 2 (3). pp. 111-113.

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The compound, 1-(2-hydroxy-4-methoxyphenyl)-3-(3 methylthiophen)prop-2-en-1-one was synthesized by using 4-methoxy-2-hydroxyacetophenone and 3-methylthiophene corboxaldehyde solutions.The reaction was monitored by thin layer chromatography (TLC) technique. The synthesized product was characterized by spectroscopically and confirmed by X-ray diffraction studies. The compound, C15H14O3S crystallizes in the monoclinic crystal class under the space group P21/c. The molecular structure exhibits intramolecular hydrogen bond of the type O--H...O. The hydrogen bonds connect the hydroxy donor group and the C=O acceptor group

Item Type: Article
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 30 Jan 2012 10:30
Last Modified: 30 Jan 2012 10:30

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