Antibacterial Potential of Leaf Extracts from Kirganelia Reticulata Baill

Shruthi, SD and Ramachandra, YL and Rai, Padmalatha S and Shetty, Veena A (2010) Antibacterial Potential of Leaf Extracts from Kirganelia Reticulata Baill. International Journal of Pharma Research and Development, 2 (6). pp. 974-981.

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Abstract

The in vitro antibacterial activity of crude methanolic, chloroform and hexane extracts of the leaves of Kirganelia reticulata (Euphorbiaceae) were investigated. Susceptibility of some Gram-negative organisms (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi) and Gram-positive organism (Staphylococcus aureus) were tested. Agar well diffusion and broth dilution methods were used to determine the minimum antibacterial activity against all the tested microorganisms. The extracts exhibited antibacterial activities with zones of inhibition ranging from 9.07 - 30.10 mm, 8.17 - 24.57 mm and 5.60 - 14.67 mm for methanol, chloroform and hexane extracts respectively. Screening of crude extracts showed notable minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at concentrations of 100 to 6.25 mgml-1. The organisms were more sensitive to the methanolic extract of the leaves, where as extracts from other solvents like chloroform and hexane showed moderate to weak activity respectively. Similar results have been showed in MIC and MBC.

Item Type: Article
Uncontrolled Keywords: Antibacterial, Gram-negative organism, Gram-positive organism, Leaf extracts.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 31 Jan 2012 06:56
Last Modified: 31 Jan 2012 06:56
URI: http://eprints.manipal.edu/id/eprint/2797

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