Development and evaluation of an optical fibre-based helium - neon laser irradiation system for tissue regeneration: A pilot study

Prabhu, Vijendra and Rao, Satish BS and Rao, Nageshwara B and Aithal, Kiran B and Shenoy, Satish B and Mahato, KK (2010) Development and evaluation of an optical fibre-based helium - neon laser irradiation system for tissue regeneration: A pilot study. PRAMANA journal of physics, 75 (6). pp. 1287-1293.

[img] PDF
Pramana_article.pdf - Published Version
Restricted to Registered users only

Download (758kB) | Request a copy

Abstract

Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present study, an optical ¯bre-based helium{ neon (He{Ne) laser irradiation system was designed, developed and evaluated for optimum tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction and mean healing time. Signi¯cant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose.

Item Type: Article
Uncontrolled Keywords: Therapeutic application; optimization; tissue response; contraction.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 08 Feb 2012 10:30
Last Modified: 08 Feb 2012 10:30
URI: http://eprints.manipal.edu/id/eprint/2906

Actions (login required)

View Item View Item