Tissue microarray – a high-throughput molecular analysis in head and neck cancer

Radhakrishnan, Raghu and Solomon, Monica and Satyamoorthy, K and Martin, Leslie E and Lingen, Mark W (2008) Tissue microarray – a high-throughput molecular analysis in head and neck cancer. Journal of Oral Pathology & Medicine, 37 (3). pp. 166-176.

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With the identification of a number of novel markers having diagnostic, prognostic, and therapeutic significance, the application of tissue microarray (TMA) has become a valuable tool for validating candidate markers in cancer research. The TMA is a high-throughput technique, which allows large-scale analyses of hundreds of archival clinical tissue samples using the 'array' approach. This paper highlights briefly its robust technology, technical aspects of its construction, and the validity of the TMA results for oral pathology diagnostics by reviewing data from recent literature particularly with reference to head and neck cancer.

Item Type: Article
Uncontrolled Keywords: head and neck cancer; oral cancer; tissue microarray
Subjects: Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 17 Feb 2012 07:04
Last Modified: 22 Oct 2016 15:46
URI: http://eprints.manipal.edu/id/eprint/3000

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