Development and evaluation of an optical fibre-based helium-neon laser irradiation system for tissue regeneration: A pilot study

Prabhu, Vijendra and Rao, Satish BS and Rao, Nageshwara B and Aithal, Kiran B and Shenoy, Satish B and Mahato, K K (2010) Development and evaluation of an optical fibre-based helium-neon laser irradiation system for tissue regeneration: A pilot study. Pramana - journal of physics, 75 (6). pp. 1287-1293. ISSN 0973-7111

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Official URL: http://www.ias.ac.in/pramana/v75/v75no6.htm

Abstract

Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present study, an optical fibre-based helium-neon (He-Ne) laser irradiation system was designed, developed and evaluated for optimum tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction and mean healing time. Significant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose.

Item Type: Article
Uncontrolled Keywords: Therapeutic application; optimization; tissue response; contraction.
Subjects: Engineering > MIT Manipal > Mechanical and Manufacturing
Depositing User: MIT Library
Date Deposited: 09 Feb 2012 09:07
Last Modified: 11 Feb 2012 04:06
URI: http://eprints.manipal.edu/id/eprint/3041

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