Mateti, Udaya Venkat and Nagappa, Anantha Naik and Patha, Srikala (2011) Clinically relevant drug interactions with newer drugs: A review. The Pharma Review . pp. 71-73.

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Abstract

A clinically relevant drug-drug interaction (DDI) occurs when the effectiveness or toxicity of one medication is altered by the administration of another medicine or a substance that is administered for medical purposes. In addition to co-administration of other drugs, concomitant ingestion of Nutrients include food, beverages (including alcohol), dietary supplements or citrus fruit or fruit juice could also alter systemic exposure of drugs, thus leading to adverse drug reactions or loss of efficacy. Drug interactions being both beneficial and harmful are important to be known to provide a beneficial effect of the same or to prevent the adverse event that could be seen. This article tries to highlight the some of the clinically significant drug interactions with newer drugs.

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