Screening for antidiarrheal activity of Psidium Guajava : A possible alternative in the treatment against diarrhea causing enteric pathogens

Chanu, Thangjam Rubee and Pai, Vasudha and Chakraborty, Rituparna and Bangar, Raju and Lobo, Richard and Ballal, Mamatha (2011) Screening for antidiarrheal activity of Psidium Guajava : A possible alternative in the treatment against diarrhea causing enteric pathogens. Journal of Chemical and Pharmaceutical Research, 3 (6). pp. 961-967. ISSN 0975-7384

[img] PDF
29_JCPR-2011-3-6-961-967.pdf - Published Version
Restricted to Registered users only

Download (126kB) | Request a copy

Abstract

Psidium guajava leaves, commonly known as guava was screened against some common enteric pathogens like Escherichia coli, Shigella spp, Salmonella spp, Aeromonas spp, Staphylococcus aureus and Candida spp. The alcoholic and aqueous extracts of Psidium guajava leaves were obtained using the Soxhlet apparatus. Antimicrobial activity of the extracts were tested on Mueller Hinton Agar by the punch well technique. Significant inhibitory effects were observed against the isolates that were tested. Significant activity of ethanolic extract was observed against Vibrio, Aeromonas, Salmonella and Shigella species. Aqueous extract showed significant activity against candida and Escherichia coli. The results of the present study supported the claims of folk medicine for the use of this plant for the treatment of diarrhea. These results were encouraging and can be extrapolated further to consider the use of Psidium guajava leaf extracts as an alternative treatment option for diarrhea caused by the enteric pathogens.

Item Type: Article
Uncontrolled Keywords: Psidium guajava, leaf extracts, Antimicrobial activity.
Subjects: Health Sciences > KMCIC
Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Manipal
Date Deposited: 19 Mar 2012 04:31
Last Modified: 19 Mar 2012 04:31
URI: http://eprints.manipal.edu/id/eprint/3598

Actions (login required)

View Item View Item