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Multisystem Langerhans Cell Histiocytosis in Adult

Garg, Anubhav and *, Pramod Kumar Multisystem Langerhans Cell Histiocytosis in Adult. Indian Journal of Dermatology, 57 (1). pp. 58-60.

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Abstract

Langerhans cell histiocytosis (LCH), is a rare disorder, clinically presents with heterogeneous manifestations, and has an unpredictable outcome. Commonly seen in infancy or early childhood, the disorder is characterized by proliferation of abnormal and clonal Langerhans cell in skin, bone, lymph nodes, lungs, liver, spleen, and bone marrow. Occurrence of LCH in adults is rare. Here, we report the case of an adult with acute onset of polymorphic eruptions all over the body, which on biopsy showed features of multisystem LCH, and was confirmed by immunohistochemistry. Although multisystem LCH has a poor prognosis, our patient responded well to chemotherapy.

Item Type: Article
Uncontrolled Keywords: Adult LCH, histiocytic infiltrate, langerhans cell histiocytosis
Subjects: Medicine > KMC Mangalore > Dermatology
Depositing User: KMCMLR User
Date Deposited: 21 Mar 2012 06:31
Last Modified: 21 Mar 2012 06:31
URI: http://eprints.manipal.edu/id/eprint/3627

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