A study of renal function tests in South Indian diabetic patient population

Bhat , Ramesh M and *, Ganaraja B (2011) A study of renal function tests in South Indian diabetic patient population. Journal of Pharmacy Research, 4 (12). pp. 4470-4472. ISSN 0974-6943

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Objective : To study the renal function in chronic Diabetes mellitus in relationship to the duration and diabetic control in order to predict renal complications such as nephropathy. Methods: The study group consisted of 50 patients aged between 15 to 80 years with history of Uremia and nephropathy due to diabetes mellitus. Patients were divided into two groups on the basis of duration of diabetes I < 25 years & II > 25 and into three groups I <300 mg/dl, II 301-359 mg/ dl & III > 360 mg/dl depending on random blood sugar levels. Their age, sex, duration of diabetes and Blood pressure were recorded. Their serum creatinine, Blood urea nitrogen and random blood sugar were determined using Auto-analyzer method. Urinary protein was measured by chemical analysis.Results: Urinary Proteins showed a highly significant (p value <0.01) increase in > 25yrs group but Serum creatinine and blood urea nitrogen did not show any significant difference between <25 years & >25 years duration group. Both systolic & Diastolic blood pressures showed Very highly significant increase (P value <0.001) in > 25 years group. Serum creatinine, blood urea nitrogen & Urinary Proteins showed a highly significant (p<0.01) & very highly significant increase (p<0.001) between the 3 groups increasing linearly with Random blood sugar.Conclusion: Early detection of renal complications in diabetes mellitus such as Nephropathy is essential. Renal function tests to detect proteinuria must be performed regularly to prevent the rapid progression of renal pathology in diabetic patients

Item Type: Article
Uncontrolled Keywords: Renal function tests, Diabetic Nephropathy, duration of diabetes, random blood sugar.
Subjects: Medicine > KMC Mangalore > Physiology
Depositing User: KMCMLR User
Date Deposited: 29 Mar 2012 07:29
Last Modified: 29 Mar 2012 07:29
URI: http://eprints.manipal.edu/id/eprint/3658

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