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Urinary excretion of pseudouridine in patients with brain tumours

Manjula, Shantaram and Aroor, Annayya Rao and Annaswamy, Raja and Rao, Suryanarayana and Rao, Anjali (1993) Urinary excretion of pseudouridine in patients with brain tumours. Acta Oncologica, 32 (3). pp. 311-314.

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Abstract

Elevated urinary levels of modified nucleosides, especially pseudouridine (Y), have been observed in patients with a variety of malignant neoplasms. In this report, the urinary Y levels were estimated by high performance liquid chromatography in 93 patients with brain tumours and in 40 age and sex matched controls. The Y levels were found to be excreted in equal amounts in the control and the tumour groups. There was no significant difference in Y when patients with malignant diseases were compared with those with benign tumours. Following therapy, the Y levels remained unchanged when compared to the controls and their preoperative values. It is concluded that urinary Y concentration is not a useful marker for brain tumours.

Item Type: Article
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Neurology
Depositing User: KMC Manipal
Date Deposited: 24 Jun 2011 09:34
Last Modified: 24 Jun 2011 09:34
URI: http://eprints.manipal.edu/id/eprint/373

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