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Free Radical Reactions and Antioxidant Activities of Sesamol:Pulse Radiolytic and Biochemical Studies

Joshi, Ravi and Kumar, Sudheer M and Satyamoorthy, K and Unnikrishnan, MK and Mukherjee, Tulsi (2005) Free Radical Reactions and Antioxidant Activities of Sesamol:Pulse Radiolytic and Biochemical Studies. J. Agric. Food Chem, 53 (7). pp. 2696-2703.

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Abstract

Sesamol (from Sesamum indicum) is a dietary compound, which is soluble in aqueous as well as lipid phases. Free radical scavenging reactions of sesamol, 5-hydroxy-1,3- enzodioxole, have been studied using a nanosecond pulse radiolysis technique. Sesamol efficiently scavenges hydroxyl, one-electron oxidizing, organo-haloperoxyl, lipid peroxyl, and tryptophanyl radicals. Its antioxidant activity has also been evaluated with cyclic voltammetry. In biochemical studies, it has been found to inhibit lipid peroxidation, hydroxyl radical-induced deoxyribose degradation,and DNA cleavage. These antioxidant and free radical scavenging activities of sesamol have been reported in the paper.

Item Type: Article
Uncontrolled Keywords: Sesamol, Dietary antioxidant, Pulse radiolysis, Lipid peroxidation, Deoxyribose degradation, DNA cleavage
Subjects: Life Sciences > MLSC Manipal
Pharmacy > MCOPS Manipal > Pharmacy Practice
Depositing User: KMC Manipal
Date Deposited: 13 Jul 2011 10:22
Last Modified: 13 Jul 2011 10:22
URI: http://eprints.manipal.edu/id/eprint/503

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